Research project

TCR ligand structures

Project overview

Structural characterisation of CD1 reactive T cell receptors including gamma delta and iNKT TCRs through protein crystallography

Staff

Lead researchers

Dr Salah Mansour PhD

Associate Professor
Research interests
  • Unconventional T cells and lipid antigen recognition in human disease
  • CD1-restricted T cell immunity, including group 1 CD1, iNKT and γδ T cells
  • Molecular and structural mechanisms of CD1-mediated antigen presentation
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Other researchers

Professor Ivo Tews

Professor
Research interests
  • Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesi…
  • Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal …
  • Cancer immunology: together with Cancer Immunology at Southampton we use a structure based ap…
Connect with Ivo

Collaborating research institutes, centres and groups

Research outputs