Doctor Alex Couto Alves | University of Southampton

Publications

62 publications

Page 1 of 7

A framework for conducting GWAS using repeated measures data with an application to childhood BMI

Kimberley Burrows, Anni Heiskala, Jonathan P Bradfield, Zhanna Balkhiyarova, Lijiao Ning, Mathilde Boissel, Yee-Ming Chan, Philippe Froguel, Amelie Bonnefond, Hakon Hakonarson, Alexessander Couto Alves, Deborah A. Lawlor, Marika Kaakinen, Marjo-Riitta Järvelin, Struan F.A. Grant, Kate Tilling, Inga Prokopenko, Sylvain Sebert, Mickaël Canouil & Nicole M. Warrington, 2024, Nature Communications, 15(1)

DOI: 10.1038/s41467-024-53687-3

Type: article

Identifying 124 new anti-HIV drug candidates in a 37 billion-compound database: an integrated approach of machine learning (QSAR), molecular docking, and molecular dynamics simulation

Alexandre de Fátima Cobre, Anderson Ara, Alexessander Couto Alves, Moisés Maia Neto, Mariana Millan Fachi, Laize Sílvia dos Anjos Botas Beca, Fernanda Stumpf Tonin & Roberto Pontarolo, 2024, Chemometrics and Intelligent Laboratory Systems, 250

DOI: 10.1016/j.chemolab.2024.105145

Type: article

Novel COVID-19 biomarkers identified through multi-omics data analysis: N-acetyl-4-O-acetylneuraminic acid, N-acetyl-L-alanine, N-acetyltriptophan, palmitoylcarnitine, and glycerol 1-myristate

Alexandre de Fátima Cobre, Alexessander Couto Alves, Ana Raquel Manuel Gotine, Karime Zeraik Abdalla Domingues, Raul Edison Luna Lazo, Luana Mota Ferreira, Fernanda Stumpf Tonin & Roberto Pontarolo, 2024, Internal and Emergency Medicine, 19(5), 1439-1458

DOI: 10.1007/s11739-024-03547-1

Type: article

Fat metabolism is associated with telomere length in six population-based studies

Ashley van der Spek, Hata Karamujić-Čomić, René Pool, Mariska Bot, Marian Beekman, Sanzhima Garmaeva, Pascal P Arp, Sandra Henkelman, Jun Liu, Alexessander Couto Alves, Gonneke Willemsen, Gerard van Grootheest, Geraldine Aubert, M Arfan Ikram, Marjo-Riitta Jarvelin, Peter Lansdorp, André G Uitterlinden, Alexandra Zhernakova, P Eline Slagboom, Brenda W J H Penninx, Dorret I Boomsma, Najaf Amin & Cornelia M van Duijn, 2022, Human Molecular Genetics, 31(7), 1159-1170

DOI: 10.1093/hmg/ddab281

Type: article

Exploring the causal effect of maternal pregnancy adiposity on offspring adiposity: Mendelian randomisation using polygenic risk scores

Tom A. Bond, Rebecca C. Richmond, Ville Karhunen, Gabriel Cuellar-Partida, Maria Carolina Borges, Verena Zuber, Alexessander Couto Alves, Dan Mason, Tiffany C. Yang, Marc J. Gunter, Abbas Dehghan, Ioanna Tzoulaki, Sylvain Sebert, David M. Evans, Alex M. Lewin, Paul F. O’Reilly, Deborah A. Lawlor & Marjo-Ritter Järvelin, 2022, BMC Medicine, 20

DOI: 10.1186/s12916-021-02216-w

Type: article

Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract

Ekaterina Yonova-Doing, Wanting Zhao, Robert P. Igo, Chaolong Wang, Periasamy Sundaresan, Kristine E. Lee, Gyungah R. Jun, Alexessander Couto Alves, Xiaoran Chai, Anita S.Y. Chan, Mei Chin Lee, Allan Fong, Ava G. Tan, Chiea Chuen Khor, Emily Y. Chew, Pirro G. Hysi, Qiao Fan, Jacqueline Chua, Jaeyoon Chung, Jiemin Liao, Johanna M. Colijn, Kathryn P. Burdon, Lars G. Fritsche, Maria K. Swift, Maryam H. Hilmy, Miao Ling Chee, Milly Tedja, Pieter W.M. Bonnemaijer, Preeti Gupta, Queenie S. Tan, Zheng Li, Eranga N. Vithana, Ravilla D. Ravindran, Soon Phaik Chee, Yuan Shi, Wenting Liu, Xinyi Su, Xueling Sim, Yang Shen, Ya Xing Wang, Hengtong Li, Yih Chung Tham, Yik Ying Teo, Tin Aung, Kerrin S. Small, Paul Mitchell, Jost B. Jonas, Tien Yin Wong, Jie Jin Wang & Ching Yu Cheng, 2020, Communications Biology, 3(1)

DOI: 10.1038/s42003-020-01421-2

Type: article

Genome-wide association analysis in humans links nucleotide metabolism to leukocyte telomere length

C. Li, S. Stoma, L.A. Lotta, S. Warner, E. Albrecht, A. Allione, P.P. Arp, L. Broer, J.L. Buxton, Alexessander Couto Alves, J. Deelen, I.O. Fedko, S.D. Gordon, T. Jiang, R. Karlsson, N. Kerrison, T.K. Loe, M. Mangino, Y. Milaneschi, B. Miraglio, N. Pervjakova, A. Russo, I. Surakka, A. van der Spek, J.E. Verhoeven, N. Amin, M. Beekman, A.I. Blakemore, F. Canzian, S.E. Hamby, J.-J. Hottenga, P.D. Jones, P. Jousilahti, R. Mägi, S.E. Medland, G.W. Montgomery, D.R. Nyholt, M. Perola, K.H. Pietiläinen, V. Salomaa, E. Sillanpää, H.E. Suchiman, D. van Heemst, G. Willemsen, A. Agudo, H. Boeing, D.I. Boomsma, M.-D. Chirlaque, G. Fagherazzi, P. Ferrari, P. Franks, C. Gieger, J.G. Eriksson, M. Gunter, S. Hägg, I. Hovatta, L. Imaz, J. Kaprio, R. Kaaks, T. Key, V. Krogh, N.G. Martin, O. Melander, A. Metspalu, C. Moreno, N.C. Onland-Moret, P. Nilsson, K.K. Ong, K. Overvad, D. Palli, S. Panico, N.L. Pedersen, B.W.J.H. Penninx, J.R. Quirós, M.R. Jarvelin, M. Rodríguez-Barranco, R.A. Scott, G. Severi, P.E. Slagboom, T.D. Spector, A. Tjonneland, A. Trichopoulou, R. Tumino, A.G. Uitterlinden, Y.T. van der Schouw, C.M. van Duijn, E. Weiderpass, E.L. Denchi, G. Matullo, A.S. Butterworth, J. Danesh, N.J. Samani, N.J. Wareham, C.P. Nelson, C. Langenberg & V. Codd, 2020, American Journal of Human Genetics, 106(3), 389 - 404

DOI: 10.1016/j.ajhg.2020.02.006

Type: article

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child and adult BMI

Alex Couto Alves, N. Maneka G. De Silva, Hazel Inskip & Sheila Barton, 2019, Science Advances, 5(9)

DOI: 10.1126/sciadv.aaw3095

Type: article

Cell-type heterogeneity in adipose tissue is associated with complex traits and reveals disease-relevant cell-specific eQTLs

C.A. Glastonbury, A. Couto Alves, J.S. El-Sayed Moustafa & K.S. Small, 2019, American Journal of Human Genetics, 103 - 1024

DOI: 10.1016/j.ajhg.2019.03.025

Type: article

Interethnic analyses of blood pressure loci in populations of East Asian and European descent

F. Takeuchi, M. Akiyama, N. Matoba, A.D.S. Couto Alves & et al, 2018, Nature Communications, 1 - 16