Research project

Combined Approach to Response Evaluation in ADHD

Project overview

The 3i-lab for Individualised and Inclusive Interventions in mental health is devoted to developing strategies to support more tailored and cost-effective interventions. 

 

Part of the Centre for Innovation in Mental Health, the 3i-lab brings together a multidisciplinary team across Psychology, Psychiatry and Engineering and has been developed with the support of NIHR (NIHR Advanced Fellowship, NIHR305518, CI: Dr Valeria Parlatini). 

 

We are currently setting up a new study aiming at testing a new method to select medication for Attention-Deficit/Hyperactivity Disorder (ADHD) based on individual pre-treatment characteristics.

 

ADHD is very common and people with ADHD often wait years to start treatment. Although ADHD medications, such as methylphenidate (MPH), are generally effective, response may vary from person to person. 

If MPH, the most commonly used first line ADHD medication, does not work, clinicians will try other medicines, one by one. This approach is expensive and delays getting the right treatment, as it can take months to find the right medication for an individual with ADHD. 

In this study, we want to predict who is going to benefit from MPH or not in the longer term, based on pre-treatment clinical, cognitive and physiological characteristics. 


If this approach works, it could help people with ADHD receive effective treatment sooner.

 

 

 

 

We are currently recruiting children, adolescents and adults from existing ADHD waiting lists at participating NHS clinics only (Hampshire and Isle of Wight Healthcare NHS Foundation Trust and South London and Maudsley NHS Foundation Trust).

 

If you have been redirected here via the advertising poster in your clinic, and you or your child would like to take part in this research, please contact our team at: 

 hiowh.careadhd.study@nhs.net

Please note that we will not be able to recruit participants from other NHS Trusts.  

 

 

 

This project also offers ample opportunities for patient and public involvement and engagement (PPIE).

If you are 16y plus and are interested, please contact us explaining in a brief paragraph why you are interested and your prior experience in PPIE work. You can email us at: hiowh.careadhd.study@nhs.net.

Staff

Lead researchers

Dr Valeria Parlatini MD, PhD, MRCPsych

Associate Professor
Research interests
  • ADHD
  • Predictors of treatment response 
  • Neuroimaging
Connect with Valeria

Other researchers

Professor Sam Chamberlain MB/BChir, PhD, MRCPsych

Professor of Psychiatry
Research interests
  • Clinical conditions of interest include Impulsive/Compulsive Disorders; such as but not limit…
  • My work also explores mental health and well-being of university students.
Connect with Sam

Dr Nathan Huneke MBChB MRes PhD MRCPsych

NIHR Academic Clinical Lecturer
Research interests
  • Experimental medicine
  • Neuroimaging
  • Placebo and nocebo effects
Connect with Nathan

Collaborating research institutes, centres and groups

Research outputs