The course provides an insight into how molecular studies can be employed to further medical research and aid in the development of novel treatments and therapeutics. The course will cover a number of areas including the analysis of genetic diseases, amyloid diseases, the role of kinases in cancer, molecular understanding of diabetes, viral and bacterial infections.
The extraction and characterization of ancient molecules and the measurement of stable and radioactive isotopes has revolutionized archaeology over the past two decades and remains at the cutting edge of archaeological science. From the identification of chemical signatures of past foods to the ability to track an individual's movement on a month by month basis, new pictures of the past are emerging as a result of archaeology at the atomic and molecular level. This module aims to give you an understanding of these cutting edge techniques and their application, along with an ability to critically appraise their results.
The organisation of the eukaryotic cell has always fascinated researchers. This module illustrates the upkeep of cellular structure and function.
This module provides fourth year students with an introduction to the molecular basis of receptor pharmacology. The module detailed analysis of the mechanisms of drug action at the molecular level through the application of biochemical and molecular biological techniques. Receptor binding, isolation and the application of molecular cloning methods are surveyed. Detailed examples will examine the molecular details of muscarinic, adrenergic, dopaminergic and excitatory amino acid receptors, neurotransmitter transporters and voltage-gated ion channels.
The module is concerned with a detailed study of the mechanisms of drug action at the molecular level by application of biochemical and molecular biological techniques. Receptor binding, isolation and the application of molecular cloning methods are surveyed. Detailed examples will examine the molecular details of GPCR, GABAergic and excitatory amino acid receptors, neurotransmitter transporters and voltage-gated ion channels.
Most biological processes involve interactions between macromolecules. It is the aim of this module to illustrate the nature of these interactions with selected examples.
