About
I investigate the evolution and function of cellular and metabolic pathways in microbial eukaryotes, including marine phytoplankton, symbionts and parasites. My research combines computational and experimental approaches to uncover fundamental principles of eukaryotic biology. I hold a joint appointment at the Czech Academy of Sciences.
Research
Research groups
Research interests
- Evolutionary cell biology
- Cellular metabolism and photosynthesis
- Parasitism and symbiosis
- Marine phytoplankton
- Bioluminescence
Current research
Current research combines comparative genomics, evolutionary biology, molecular biology, and biochemistry to uncover the origins and functions of poorly understood cellular and metabolic pathways in microbial eukaryotes. Ongoing projects investigate bioluminescence in marine dinoflagellates, phosphorus metabolism, photosynthetic pigments, harmful algal blooms, and parasite biology. Experimental work uses Phaeodactylum tricornutum, Chlamydomonas reinhardtii, and Tetrahymena thermophila as model systems.
Research projects
Active projects
Publications
48 publications
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Jan Janouškovec, Denis V. Tikhonenkov, F Burki, Alexis T. Howe, Forest L. Rohwer, Alexander P. Mylnikov & Patrick J. Keeling,
2017, Current biology : CB, 27(23), 3717-3724
Type: article
Jan Janouškovec, Gregory S. Gavelis, Fabien Burki, Donna Dinh, Tsvetan R. Bachvaroff, Sebastian G. Gornik, Kelley J. Bright, Behzad Imanian, Suzanne L. Strom, Charles F. Delwiche, Ross F. Waller, Robert A. Fensome, Brian S. Leander, Forest L. Rohwer & Juan F. Saldarriaga,
2017, Proceedings of the National Academy of Sciences, 114(2), 171-180
Type: article
Jan Janouskovec & Patrick J. Keeling,
2016, Current Biology, 26(4), R174-R177
Type: article
KV Mikhailov, DV Tikhonenkov, J Janouškovec, AY Diakin, MV Ofitserov, AP Mylnikov & VV Aleshin,
2015, Biochemistry (Moscow), 80, 1492-1499
Type: article
Denis V. Tikhonenkov, Jan Janouskovec, Patrick J. Keeling & Alexander P. Mylnikov,
2015, The Journal of Eukaryotic Microbiology, 63(2), 220-232
DOI: 10.1111/JEU.12271
Type: article
Yong H. Woo, Hifzur Ansari, Thomas D. Otto, Christen M. Klinger, Martin Kolisko, Jan Michalek, Alka Saxena, Dhanasekaran Shanmugam, Annageldi Tayyrov, Alaguraj Veluchamy, Shahjahan Ali, Axel Bernal, Javier del Campo, Jaromir Cihlar, Pavel Flegontov, Sebastian G. Gornik, Eva Hajduskova, Ales Horak, Jan Janouskovec, Nicholas J. Katris, Fred D. Mast, Diego Miranda-Saavedra, Tobias Mourier, Raeece Naeem, Mridul Nair, Aswini K. Panigrahi, Neil D. Rawlings, Eriko Padron-Regalado, Abhinay Ramaprasad, Nadira Samad, Ales Tomcala, Jon Wilkes, Daniel E. Neafsey, Christian Doerig, Chris Bowler, Patrick J. Keeling, David S. Roos, Joel B. Dacks, Thomas J. Templeton, Ross F. Waller, Julius Lukes, Miroslav Obornik & Arnab Pain,
2015, eLife
DOI: 10.7554/ELIFE.06974
Type: article
J Janouškovec, DV Tikhonenkov, F Burki, AT Howe, M Kolísko, AP Mylnikov & PJ Keeling,
2015, Proceedings of the National Academy of Sciences of the United States of America, 112(33), 10200-10207
Type: article
P Flegontov, J Michálek, J Janouškovec, De-Hua Lai, M Jirků, E Hajdušková, A Tomčala, TD Otto, PJ Keeling, A Pain, M Oborník & J Lukeš,
2015, Molecular Biology and Evolution, 32(5)
Type: article
William A. Kirby, Denis V. Tikhonenkov, Alexandre P. Mylnikov, Jan Janouskovec, Gordon Lax & Alastair G. B. Simpson,
2014, The Journal of Eukaryotic Microbiology, 62(2), 227-238
DOI: 10.1111/JEU.12172
Type: article
KV Mikhailov, J Janouškovec, DV Tikhonenkov, GS Mirzaeva, AY Diakin, TG Simdyanov, AP Mylnikov, PJ Keeling & VV Aleoshin,
2014, Genome Biology and Evolution, 6(9), 2361-2367
DOI: 10.1093/gbe/evu186
Type: article
Biography
Jan obtained his BSc and MSc degrees from the University of South Bohemia, where he contributed to the discovery of a novel alga closely related to apicomplexan parasites. He continued his work on the evolution of apicomplexan parasitism and plastid organelles during his PhD at the University of British Columbia, which he completed in 2013.
Jan subsequently held independent fellowships at San Diego State University (CIFAR Global Scholar, 2014-2015) and University College London (Excellence Research Fellow, 2016-2019), where he discovered new lineages of eukaryotes and investigated the evolution of phytoplankton. In 2021, he established a research group at the Institute of Microbiology in Třeboň, Czechia, and later joined the School of Biological Sciences at the University of Southampton as a Lecturer. He currently leads a research programme spanning Southampton and the Czech Academy of Sciences.